The End of Alzheimer's by Dale Bredesen, M.D.
MUST BUY.... MUST READ.... KEEP FOR REFERENCE
This book is nothing short of miraculous. Until Dr. Bredesen's ReCODE, there was no drug, no therapy, no hope for a diagnosis of Alzheimer's. Not that the pharmaceutic industry didn't try; after investing billions of dollars, the only two FDA approved drugs for Alzheimer's make the patients worse. This miracle will help millions of humans and save our health care system.
Chapter 4 on How to Give Yourself Alzheimer's: A Primer: will give everyone pause.
Alzheimer's is not a single disease. Dr. Bredesen divides Alzheimer's into:
Type 1: Inflammatory – HOT characterized by increased C-reactive protein, a decrease in the ratio of albumin to globulin, an increase in interleukin-6, an increase in tumor necrosis factor and accompanying metabolic and hormonal abnormalities such as insulin resistance.
Type 2: Atrophic – COLD typically presents with the inability to form new memories even as the ability to speak, write and calculate are retained. Levels of hormones including thyroid, adrenal, estrogen, progesterone, testosterone, and pregnenolone are usually suboptimal. Vitamin D is often reduced. Insulin resistance may occur, or insulin levels may be too low. Homocysteine may be high (also in Type 1).
Type 1.5: Glycotoxic – SWEET characterized with chronically high glucose levels with the glycation of proteins and inflammation in Type 1 but also insulin resistance so that insulin no longer acts a neurotrophic chemical as in Type 2.
Type 3 Toxic – VILE occurring more commonly in non ApoE4 carriers (ApoE3), later in life, often after great stress, beginning with cognitive difficulties involving numbers or speech or organizing.
As you will see from the book, every single patient is different. Testing is only way to differentiate the best efforts to avoid or reverse the disease.
For our patients, volunteers and donors who are already following The Path to Health, much of ReCODE will look familiar; please do not mistake this overlap and dismiss this book, it is that important.
Retinal imaging has the opportunity to be of assistance in the quest for Brain Health. NeuroVision Imaging is noted in the book using curcumin to autofluoresce retinal lesions . Wide field retinal imaging has noted more narrowing of retinal vessels in the periphery in “Alzheimer's patients”. We know, much like the pharmaceutic efforts, that we are dealing with a variety of diseases. We at the Stingl Eye Clinic are committed to offering ReCODE and disseminating the knowledge to eliminate Alzheimer's disease.